LONDON- Researchers at Bristol University, England discovers a link between child asthma at age three and exposure to paracetamol in pregnancy.
Pregnant women who take paracetamol are more likely to have babies who develop asthma, suggests a new study.
Researchers showed that asthma can be linked to pregnant women and babies being exposed to paracetamol by testing the association was not simply due to the complaint the woman is taking the over the counter pill.
Co-author Doctor Maria Magnus, of Bristol University, said: “Uncovering potential adverse effects is of public health importance, as paracetamol is the most commonly used painkiller among pregnant women and infants.”
Researchers in Norway and Bristol compared associations between several conditions during pregnancy – with and without the use of paracetamol – and asthma developing in the 114,500 children in the Norwegian Mother and Child Cohort Study.
They examined asthma outcomes at ages three and seven and evaluated the likelihood of the association being as a result of the three most common triggers for paracetamol use in pregnancy: pain, fever, and flu.
The results, published in the International Journal of Epidemiology, showed that 5.7 per cent of the children had asthma at age three, and 5.1 per cent had asthma at age seven.
The research found a consistent link between children having asthma at age three and having been exposed to paracetamol during pregnancy.
The strongest association was seen if the mother used paracetamol during pregnancy for more than one complaint with a child having asthma at three-years-old.
Overall, the findings indicated that prenatal paracetamol exposure showed an independent association with asthma development. The association was similar whether used for flu, fever or pain.