Rome: A new Italian scientists has revealed that eating less may keep the mind young and said that they have discovered the molecular process by which a strict diet may save the brain from the ravages of age.
The research, published in the US journal the Proceedings of the National Academy of Sciences, is based on a study of mice that were fed a diet of about 70% of the food they normally consumed.
Scientists found the calorie-restricted diet triggered a protein molecule, CREB1, that activates a host of genes linked to longevity and good brain function.
“Our hope is to find a way to activate CREB1, for example through new drugs, so to keep the brain young without the need of a strict diet,” said lead author Giovambattista Pani, researcher at the Institute of General Pathology, Faculty of Medicine at the Catholic University of Sacred Heart in Rome.
Researchers have previously discovered that mice on diets showed better cognitive abilities and memory, less aggression, and tended to avoid or delay Alzheimer’s disease. But they have not known exactly why.