Ikhtiar is the fourth regime insider to die as a result of the attack at the national security bureau.
The announcement of Ikhtiar’s death came as the other victims of the bomb attack were buried.
The other three high-profile victims were the defence minister, his deputy who is also Assad’s brother-in-law, and a former defence minister.
Meanwhile, Russia’s envoy to France has sparked a row with Damascus after suggesting President Bashar al-Assad was ready to step down.
Alexander Orlov said Mr Assad had, in effect, agreed to step down last month at a conference in Geneva which had planned for a democratic transition.
“Assad nominated his representative to lead the negotiations with the opposition for this transition. That means he accepted to leave, but in a civilised way,” said Mr Orlov.
His comments triggered an angry response from Syria, where the information ministry said the claims were completely baseless.